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Search Term: " chlorogenic acid "
The Various Health Benefits of Moringa Oleifera   
Date:
September 20, 2022 11:04 AM
Moringa Oleifera is a tree that is native to India, Pakistan, and Bangladesh. For centuries, it has been used as a food source because of its many nutrients. It is only recently that studies have been done to confirm the health benefits that are attributed to the tree. These benefits are a result of the numerous bioactive components that are naturally occurring in Moringa, including phenolic acids, flavonoids, isothiocyanates, tannins, and saponins. Some of the potential health benefits of consuming Moringa Oleifera include: 1) Boosts immune system – This is due to the presence of vitamins and minerals such as Vitamin C, Potassium, and Zinc.* 2) Regulates blood sugar levels – This is beneficial for those who suffer from diabetes.* 3) Reduces inflammation – This can help with conditions such as arthritis.* 4) Protects against bacterial infections – This is due to the presence of compounds such as Quercetin and chlorogenic acid.* 5) Aids in digestion – This is due to the presence of fiber.* 6) Increases energy levels – This is due to the presence of Vitamin B6.* 7) Improves cognitive function – This is due to the presence of Rutin.* 8) Moisturizes skin – This helps to keep skin looking young and healthy.* In Summary: Moringa Oleifera has a multitude of health benefits that have been attributed to its naturally occurring bioactive components. It is important to consume organic moringa leaf in order to reap these benefits. NOW uses only non-GMO organic moringa leaf in their products. By adding this superfood into your diet, you can improve your overall health and well-being.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6455) Is Apple Juice Acidic or is it Good for Acid Reflux? 
Date:
July 06, 2017 09:14 AM
Some people might wonder if apple juice is acidic or if it is bad for acid reflux. Apple juice is very delicious and refreshing. It contains good amounts of vitamins and minerals. It is very rich in vitamin C and it provides 159% of the recommended intake. Most of the fruit juices that have an acidic quality have a low PH. For example, the PH of apple juice varies from 3.35 to 4, which is interesting. Key Takeaways:
"Is apple juice good for acid reflux? No, in fact consuming acidic juices like apple juice may worsen acid reflux." Read more: http://www.foods4betterhealth.com/is-apple-juice-acidic-35901
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4933) Does Green Coffee Bean Extract Help With Weight Loss?
Date:
December 12, 2012 10:56 AM
Green coffee beans Green coffee beans are the seeds of a coffee plant that have not been roasted and usually have a high content of chlorogenic acid, which play a critical role in metabolic reactions in the body. It helps to break down fats, promote carbohydrate absorption, control the levels of blood sugar and also act as an antioxidant. Coffee beans are usually soaked and then concentrated to be able to get the green coffee extract. Clinical studies have shown that daily intake of about 400 mg of the coffee bean extract before taking breakfast allow one to lose one pound every week without altering the diet. This is explained by the ability of chlorogenic acid to burn out fat. A certain research also showed that taking 700mg of these extracts once a day enables one to lose weight daily. These clinical studies have been backed up by reviews from people who have used the green coffee extract. chlorogenic acid is a plant polyphenol with a variety of antimicrobial properties and ability to suppress the absorption of glucose leading to weight loss. Roasted coffee beans usually have a very low chlorogenic acid concentration which breaks down during roasting of the beans. Antioxidant properties Researches have shown that this acid is a tumor inhibitor by nature, and it does this by preventing carcinogenic agents from integrating with DNA and resulting in cancer. It has been proven to prevent cardiovascular diseases, atherosclerosis, and type II diabetes. Most supplements of green coffee have piperine and green tea, and other contents that focus on burning fats. When buying green coffee extract, establish all the contents and the effect. One should not drink much coffee. There is no need for coffee, one will get all the nutrients including a small amount of caffeine as an energy boost, so extra coffee might just amp you up to much.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2748) Green Coffee Bean Extract
Date:
November 22, 2012 10:31 PM
Many studies have been carried out to establish the health benefits of Green coffee bean extract for several years. It was just in 2012 that some group of scientists revealed a particular study that demonstrated Green Coffee Bean Extract‘s effectiveness in contributing to weight loss. Leading this study was Dr Joe Vinson, a scientist from the University of Scranton. On the same note, sixteen over-weight people also participated in the study. They were all given varying doses of the Green Coffee Bean Extract for a period of 22 weeks. These participants lost around 17 pounds when the study ended. They did not report any side effect. Moreover, they were under no exercise plan or diet change during the period of study. The coffee powder that people normally use is prepared after roasting some green coffee beans. The extract is obtained from green coffee bean at a temperature of about 70°C for 2 hours using 70 percent of ethanol. A green coffee bean extract is a yellowish brown hygroscopic powder that has high polyphenols levels referred to as hydroxycinnamic acids, which contains caffeic and chlorogenic acids. Green coffee bean extract and weight loss A Japanese scientist, known as Hiroshi Shimoda, did a research about the green bean extract and discovered that it facilitates body weight loss. The weight loss is brought about by some two natural chemical compounds found in the green coffee bean. Since coffee beans are not roasted, they still have their natural chemicals that can otherwise be lost if they are roasted. The two natural chemicals are chlorogenic acid and caffeine which jointly lead to loss of weight. The caffeine in coffee works by stimulating the release of fatty acids from the fats stored inside the body. The chlorogenic acid, on the other hand, helps the liver to process the released fatty acids thus resulting in weight loss. If one consumes 1kg of food containing 10g of green bean extract daily for 14 days, then the increase in weight can be suppressed by about 35 percent. Other Health Benefits of Green coffee bean extract Anti-aging Benefits The chlorogenic acids in green coffee bean destroy any free radicals formed within the body through metabolism. If such free radicals are left, they can destroy the cell membrane and trigger some ageing symptoms. By destroying such harmful radicals, green coffee bean extract actually slows down the natural aging process. Some studies also reveal that the absorption capacity for oxygen radicals by the green coffee extract is twice that of green tea or grape seed extracts. Reduce Blood Pressure Animal research also reveals that chlorogenic acids in the green bean extract helps in alleviating high levels of blood pressure. Considering the results of this particular study, some research was further conducted on human beings. This experiment, performed on people with mild hypertension, revealed that the consumption of the green coffee extract supplement contributed in lowering high blood pressure levels. When a dose of about 185mg of green coffee extract supplement was consumed, the extract proved quite effective in reducing symptoms of hypertension. Hence they are often used for the treatment of the same.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2734) What Are The Health Benefits Of Rhodiola Rosea?
Date:
February 26, 2012 07:02 PM
Rhodiola Rosea: Rhodiola rosea is medicinal herb that has many beneficial health effects on humans. It grows in the cold regions of the world like Europe, Central Asia and Arctic region. The phytochemicals present in this medicinal plant are good antioxidants and they are quercetin, chlorogenic acid, gallic acid and proanthocyanidins. It also consists of essential polyphenols namely rosiridin, rhodioniside and rhodiolin in the extracts of Rhodiola. These substances are the active ingredients of this herb and helps in improving the overall health of the body. The extracts of this plant can be taken in the form of tea, pills or liquid form and must be taken after prescription by medicinal health expert. Some of the health benefits of Rhodiola rosea plant are explained as follows Stabilize the Nervous system: This nature gifted herb is very helpful to stabilize the levels of neurotransmitters in our brain and thereby increase the levels of tryptophan, dopamine and norenephrine in our body naturally. Thereby, improve the neuro-chemical reactions inside the body.A Good Anti-oxidant: It acts as a good antioxidant and also protects our nervous system. It helps to overcome the damage caused to nervous system by eliminating the free radicals present in our body. Treat Depression: It is known though a scientific research that Rhodiola rosea gave good results to treat mild and moderate depression on people of age group from 18 years to 70 years. The prescribed dosage to get the complete health benefit is 340 mg to 680 mg per day. SHR-5, the extract of this plant enhances the mental performance and also helps the person to concentrate on healthier subjects. This medicinal herb can also be used along with other anti-depressant drugs as it has the synergistic effect. Regular intake of the plant's extract according to the prescribed dosage by expert doctor reduced the symptoms of fatigue and helped them improve their concentration power. This herb is being used in cold counties like Scandinavia and Russia to overcome the stressful life and chill climate. Improves the Overall Health: This medicinal herb is known to enhance the immune system of a person and also improve the overall health. It helps in preventing the side-effects of stress and improve the physical activity, enhance the mood, appetite, estrus cycle, reduce fatigue etc. It also helps to overcome stress, anxiety, anemia, hormonal imbalance cardiovascular diseases, and neurological disorders of a person. It is also known to decrease the time needed for recovery after any strenuous muscular activity. Treat Insomnia: It is also being used to treat Insomnia and has given good results. Sleeplessness can be cured effectively with this herb without any side effects. Pregnant women and breastfeeding mothers should not take this medicinal herb as it has some side effects on them. Always consult your medicinal health expert before taking the extracts of this herb and take the correct dosage.It is known to maintain creatine phosphate at high levels and this is especially useful for athletes to maintain their stamina levels. Rhodiola rosea is also used to overcome the side effects of radiation therapy and chemotherapy.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2594) BerryOxidants - Food-Sourced Antioxidant Protection
Date:
April 12, 2009 11:07 AM
BerryOxidants - Food-Sourced Antioxidant Protection
2 tablets contain: Vitamin C (as ascorbic acid) 1,000 mg Grape Seed Extract (Proanthodyn™) 150 mg Green Tea Leaf Ext (95% polyphenols, 150 mg 35% ECGC) Turmeric Rhizome Ext (95% curcumin) 150 mg Polygonum cuspidatum Root Ex 100 mg (8% total resveratrols) Bromelain 100 mg Quercetin 100 mg Ginkgo Leaf Extract (50:1) 60 mg 24% Flavoneglycosides Silymarin (from milk thistle seed ext) 60 mg Hawthorn Berry Extract (4:1) 50 mg Rosemary Leaf Extract (5:1) 50 mg Citrus Bioflavonoids 50 mg Lecithin 50 mg Grape Skin Extract (20% polyphenols) 50 mg Astragalus Root Extract (10:1) 50 mg Cabbage Floret & Stem 50 mg Cranberry Fruit Ext (90% solids) 50 mg Sweet Cherry Fruit Ext (10:1) 50 mg Holy Basil Leaf Ext (2% ursolic acid) 50 mg Olive Leaf Ext (15% oleuropein) 40 mg Rutin 40 mg Lycium Fruit Extract (4:1) 40 mg Strawberry Fruit 40 mg Açai Fruit Juice Powder 40 mg Organic Amla Fruit 40 mg Pomegranate Seed Ext (40% elagitannins) 20 mg European Elder Berry Ext (5% flavones) 20 mg Mangosteen Fruit Rind Extract 20 mg (standardized to 95% flavonoids & 40% mangostins) Raspberry Leaf Ext (40% elagitannins) 10 mg White Mulberry Fruit Ext (10:1) 10 mg Blueberry Leaf Ext (20% chlorogenic acid) 10 mg Bilberry Fruit Ext (25% anthocyanidins) 5 mg
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1992) Green Coffee Bean Extract
Date:
October 22, 2008 04:59 PM
It is known that aging is largely a result of the effect of free radicals on our body cells, and that green coffee bean extract can be used to fight against these. While we intuitively understand what the term ‘aging’ means, very few people can actually describe it in words, although there are several theories of why it occurs. The most viable of these include the Error Catastrophe Theory, related to faulty molecular transcription and errors in cellular function, the Crosslinkage Theory, in which progressively increasing cross-linking between proteins slows the body functions down, and the Neuroendocrine Theory, in which changes in homeostasis and hormone levels occur through time due to an increasing loss of sensitivity of receptors to feedback inhibition. However, by far the most acceptable and best understood theory is the Free Radical Theory of Aging, which green coffee beans have been found to help fight, and it is on that which we shall focus here. The Free Radical Theory of Aging Free radicals are oxidants created by unpaired electrons. Electrons generally go around in pairs, but occasionally molecules lose one of these electrons, creating a situation where it possesses an unpaired electron. In this condition, that molecule has only one purpose in life and that is to oxidize other molecules by stealing an electron from them. Oxidation can cause untold damage to cell membranes, and also to other molecules that are vital to life, such as DNA. The end result is aging, and the onset of many diseases and conditions connected with aging. Free radicals are believed to be behind inflammatory diseases such as arthritis and Crohn’s disease, strokes, cardiovascular disease, Parkinson’s disease, Alzheimer’s disease and cancer among many others. Each of these is associated with aging. Free radicals are generated in the body in four different ways: 1. Energy is generated by the intercellular mitochondria by the production of ATP (adenosine triphosphate). By-products of the mechanism by which this is done include hydrogen peroxide, the superoxide anion, and a hydroxyl radical. Over 20 billion molecules of antioxidant are produced in each individual cell daily, and every one of these has the capability to do damage to your body. The figure for inefficient cell metabolism is significantly higher. 2. Peroxisomes are eukaryotic cell components that contain oxidative enzymes, whose function is to produce hydrogen peroxide that is then used by another enzyme, catalase, to oxidize other toxic substances. It is used by the liver, for example, to oxidize about a quarter of all the alcohol we drink to acetaldehyde, and also to remove other toxins from the body. The down side is that the hydrogen peroxide can escape and degrade the cell membranes. 3. Chronic infections give rise to a high activity of white blood cells, which utilize oxidants of various kinds to destroy viruses, bacteria and parasites. These include hydrogen peroxide, superoxide and nitric oxide which can also destroy the cells they are protecting. 4. Cytochrome P450 is an enzyme used to clear the body of toxic chemicals in our food such as pesticides and drugs. They also give rise to oxidative by-products. In addition to these, free radicals are also produced by air pollution consisting of smoking, factory emissions and traffic fumes. Trace metals such as lead, iron and copper, are rich free radical sources, as is the ultraviolet component of sunlight, and caffeine, from tea and coffee, can also contribute to the store of free radicals in your body. So where does green coffee extract come into this, and how should it be used. Free radicals tend to react very rapidly to accelerate aging, and in order to counter them, and hold the effects of aging at bay, it is necessary to destroy them almost as quickly as they are produced. This is carried out by antioxidants, of which there must be a plentiful supply available in each body cell. Antioxidants donate electrons to free radicals, and so effectively neutralize them before they can attack the membranes of the cells in your body, or any of the other tissues that they can degrade. Many of the vitamins have a powerful antioxidant effect, among them vitamins A, C and E. Other antioxidants available in our diet include beta carotene and other carotenoids, flavonoids and glutathione, and also cofactors such as lipoic acid. All of these can destroy free radicals by the donation of an electron. Green coffee beans have also been found to possess a strong antioxidant effect, due largely to the plant phenols, such as caffeic acid that forms chlorogenic acid with quinic acid, both cholorgenic and caffeic acid being string antioxidants. Green coffee bean extract is standardized to 99% chlorogenic acid. This substances not only reacts rapidly with free oxygen radicals but also helps to prevent to formation of hydroxyl radicals. It has been established that green coffee bean reacts twice as fast as green tea or grape seed extracts, and speed of reaction is critical in the destruction of free radicals that have to be destroyed before they do damage. Other antioxidants found in extracts of green coffee beans include heterocyclic compounds such as pyrroles, furans and maltol. The extract is made from beans of Coffea Arabica, this containing higher concentrations of chlorogenic and caffeic acids than the Arabica plant. The extract is also produced to be naturally low in caffeine, thus avoiding the negative effects of drinking coffee for its stimulating properties. When the green coffee bean is roasted, the antioxidant effect is found to decrease, and after roasting and brewing both the Arabica and the Robusta beans have reduced in activity to much the same level. Studies on some of the conditions exacerbated by free radicals have indicated the effectiveness of green coffee beans as an antioxidant. It is believed to help reduce atherosclerosis caused by the oxidation of low density lipids (LDL). Oxidized LDLs tend to be easily absorbed by phagocytes to form plaques and foam cells in artery walls, thus narrowing and hardening the arteries, causing a deprivation of oxygen and nutrients to the heart and also increased blood pressure. Antioxidants from the green coffee bean prevent this from happening, and so help to reduce this serious effect of aging. A good supply of antioxidants will also prevent the cell membranes from being destroyed, one effect of which is to age the skin. Antioxidants in the form of green coffee bean extract can help to maintain a youthful appearance while also aiding in the prevention of the more serious effects of free radicals that can shorten life. There are no doubts that free radicals contribute significantly to accelerated aging, and that the antioxidants contained in green coffee beans can help hold back the physical signs of aging, while also helping to destroy those free radicals that threaten life by promoting cancer, atherosclerosis, and other similar conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1922) Artichoke Promotes Healthy Fat Digestion and Metabolism
Date:
January 30, 2008 10:37 PM
In discussing the health benefits of the artichoke, and the way it promotes healthy fat digestion and metabolism, we are talking here about the true artichoke: the globe artichoke. The alternative Jerusalem artichoke is not an artichoke at all, but a member of the sunflower family. The globe artichoke is a type of thistle. It is in fact a perennial thistle that originated in the Mediterranean area and is now cultivated world wide. The edible portions are the lower parts of the bracts and the base of the buds, known as the heart while the inedible portion in the center of the bud is known as the ‘choke’. Globe artichokes were introduced to the USA in the 19th century by French and Spanish immigrants who settled in Louisiana and California respectively. Contrary to popular opinion its name did not come from the ‘heart’ and the ‘choke’, but from the Arabic for ground thorn: ‘ardi shauki’. In today’s world of fast foods, a high consumption of fats and red meat and excessive alcohol consumption, your liver is put under a great strain. Its main function is as a chemical factory, to produce the chemicals, such as enzymes and other proteins, needed to maintain life and also to metabolise the nutrients we need from the food we eat. If you overtax your liver it will not work as it should, which results in poor digestion and assimilation of the nutrients in your food and an increase in the toxins in your blood. You will feel tired and run down, with digestion problems and many other health complaints. Liver abuse can result in malnutrition, which also results in cirrhosis which is not curable. You should seriously appraise your diet, and identify the eating and drinking habits that are causing the problem, and give your liver a rest. Artichoke extract is a great liver tonic, and your liver will respond well to a break from alcohol and fatty foods, and a course of artichoke leaves and extract. The main active ingredient of the artichoke is cynarine (1,5-dicaffeylquinic acid), a substance that stimulates the production of bile, and hence renders the artichoke an excellent starter for any meal. This is yet another example of science finding a logical reason for people eating artichokes for centuries in order to promote the health of their liver and digestive system. It is not only for its cynarine content that the globe artichoke is useful, however, but also the luteolin and chlorogenic acids that it contains. The stimulation of bile production by the cynarine is one the more important of the effects of artichoke on your well being. Bile emulsifies fats and renders them into an easily digested form. Most of the digestive chemicals are water soluble, and without this emulsification of the fat with water then most of the fats we consume would pass through the body unchanged. We would the vats majority of the fat soluble nutrients in our food, including vitamins A, D, E and K. Bile enables us to digest fats and to absorb vitamins from our food, and also promotes the general health of our digestive system. It is biosynthesized in the liver from various enzymes and triglycerides and then stored in the gall bladder until needed. Its use is prompted by the presence of fats in the system, and this is stimulated by the cynarine in the artichoke leaves. Its ability to improve bile flow has been recognized by scientist’s world wide, and artichoke juice has been used by the French for many years as a liver tonic. However, it is not just for the liver and the digestive system that artichokes are useful in maintaining good health. They also have an effect on the cholesterol levels in your blood. This is believed to be due to the inhibition of the activity of enzyme HMG CoA Reductase that helps the liver to generate cholesterol. Inhibiting the activity of this enzyme reduces the amount of cholesterol produced. This can have the effect of reduced the possibility of you developing atherosclerosis, a condition caused by deposition of low density lipid (LDL) cholesterol through the effect of free radical oxidation of the lipid. The less cholesterol to be transported by your blood, then the lower levels of the low density lipid needed to do this. This effect is also possibly due to the fact that bile is formed from cholesterol and triglycerides, and so stimulated bile production would possibly leave less cholesterol in the bloodstream. Artichoke also possesses antioxidant properties that would contribute even further to this effect by preventing the oxidation of the LDL by free radicals. These free radicals, formed in the body both naturally and by the effects of pollutants such as pesticides, cigarette smoke and traffic fumes, are destroyed by antioxidants. In atherosclerosis the LDL lipids are oxidised and deposited under the surface cells of the blood vessels, and are then digested by certain blood cells forming a hard fatty deposit that can eventually block the arteries affected. The result can be a heart attack or a stroke, depending on where in the body the blood vessels are affected, and if the cholesterol levels in the body are decreased through it being used to produce bile, then the concentration of LDL lipids used to transport it will also be reduced and the condition will be less likely to occur.. Apart from the liver, the gall bladder is also given a boost by artichoke because that is where bile is stored, and a regular flow to and from the gall bladder maintains its health. The only thing you should be aware of if is that if you are prone to gallstones then the increase in bile flow could cause the stones to be stuck in the bile duct. You should therefore refer to your physician before embarking on a course of artichoke extract if you have a propensity to develop gallstones. Apart from the phytonutrients already discussed, the globe artichoke also contains a good supply of fiber and minerals such as potassium, iron, calcium and phosphorus, and also some trace elements that your body needs. It is therefore more than just a bile stimulant, but provides a wide range off essential nutrition to your body. It is know to aid conditions such as gout, high blood sugar, and digestive complaints such as flatulence, bloating and abdominal cramps. Apart from cooking and eating the tender parts of the leaves, or bracts, you can make an infusion of the parts that you don’t eat. Chop up the tougher leaves and pour boiling water over them as if making tea. Leave it to infuse for a few minutes and then drink. Honey can be used to take away the bitter taste; honey rather than sugar due to its greater nutritional content.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1710) Green Coffee For Protection Against Oxidative Stress
Date:
November 17, 2007 11:46 AM
It is recorded that coffee drinking originated in Ethiopia in North East Africa, from where Arab traders introduced the plant to the Middle East. From there it moved to Turkey in the 15th century, where it was highly prized as a daily beverage due its invigorating properties. It is also believed that the infamous Captain John Smith introduced the plant to Virginia. The Brazilian coffee trade was due largely to the introduction of the bean to that country by the French in 1727, and the Boston Tea Party of 1773 rendered it the only non-alcoholic drink worth consuming by the patriots of 18th century America. Now over 50% of Americans drink coffee daily, although this seems a somewhat conservative estimate, and the tea houses of England have largely been replaced by coffee shops and the ubiquitous Starbucks. So much for the history of a beverage that has been prized for its stimulant properties, but recent research has established that not only is coffee a stimulating drink, but that it is a strong antioxidant due to its polyphenol content. However, not all forms of coffee have this property, only the green coffee bean before it has been roasted. Polyphenols are very powerful antioxidants that scavenge the free radicals that destroy body cells, and not only accelerate aging but also threaten the health of your cardiovascular system and the health of other major organs. Free radicals are compounds with a spare electron. Normally the electrons in all stable molecules come in pairs, and any free electron without a partner is like a lovelorn bachelor. It will seek a mate, and take it from wherever it can find one. Usually it secures its partner by stealing an electron from one of our body cells. This can totally destroy the cell, as it might anybody who has its partner stolen, and cell destruction is not a good thing. It is the destruction of body cells that promotes the appearance that aging brings: the wrinkles and the loss of energy that is generated by healthy cellular activity. Antioxidants destroy these free radicals, and come in a number of different guises. Vitamins A, C and E are all powerful antioxidants, as are many of the compounds that are essential to our biochemistry such as beta carotene and polyphenols. These polyphenols are found in practically all plants to a greater or lesser degree, and another rich source is grapes, and those found in green coffee beans are what are known as hydroxycinnamic acids the most abundant of which is caffeic acid. Another is chlorogenic acid, and together they form a very potent team in preventing the oxidation by free radicals of LDL (low density lipoprotein). Low density lipoproteins are those that carry cholesterol from the liver to areas of the body that need first aid due to damage, such the arterial walls. However, this can be attacked by free radicals and oxidized which results in the deposition of excess cholesterol that can build up till it eventually constricts, and sometimes completely blocks, the major cardiac arteries. This is a serious condition known as atherosclerosis that can eventually lead to cardiac disease and arrest or to strokes if the artery is in the brain. Not only do chlorogenic and caffeic acid help to prevent this from occurring, but they also help to prevent the cellular degeneration caused by the free radicals. They must be extracted from the green coffee bean because roasting or heating in any way, including brewing, destroys them. In fact, brewed coffee contains some potentially harmful substances called diterpenes that some believe can increase your chances of coronary disease by up to fifth if you drink coffee regularly over your lifetime. It is also believed that green coffee extract can reduce the risk of diabetes due to its effect on your blood glucose levels. Evidence is coming to light that some polyphenols, including chlorogenic acid, might have inhibiting properties on the activity of glucose-6-phosphate, otherwise known as Robison Ester, which is involved in the metabolism of blood glucose and which is affected by diabetes which reduces its concentration. chlorogenic acid is though to be able to redress this imbalance and not only reduce blood glucose levels, but increase the glycogen stored in the liver as an emergency energy source for the body. Green coffee bean extract also possesses other beneficial properties, not the least of which is its effect in increasing the metabolism of fats in relation to carbohydrates. This assists in weight loss and also increases stamina. The decrease in the risk of diabetes of up to 50% in men, and slightly less in women, could be due to a combination of the regulation of glucose-6-phosphate and the regulation of blood glucose levels and glucose and weight management in general. The vast majority of diabetes patients are overweight. In animal studies, the presence of chlorogenic acid appears to reduce the hyperglycemic peak that arises through the action of glucagon, a hormone used to counter hypoglycemia. The fact that chlorogenic acid reduced this sugar peak indicates its potential use in reducing abnormally high blood glucose levels. Another effect of this was an increase in the animal’s glycogen level and in the level of glucose-6-phosphate in the liver. This indicates a reduction in glycogenolysis, by which glycogen is ultimately converted to glucose-6-phosphate and glucose, thus increasing the blood glucose levels and also of gluconeogenesis which is the production of glucose from carbohydrates and some glucogenic amino acids. In other words, green coffee bean extract can help to regulate blood glucose levels by preventing the liver from producing glucose from glycogen and carbohydrates. However, the biochemistry apart, it must be stressed that these benefits are not obtained by drinking coffee, and it has to be repeated that the active agents in providing them are destroyed by the roasting and brewing processes. It is only the green coffee beans that can be used for protection of oxidative stress of human body cells and the gradual degradation into premature aging and many other related conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1635) Complete Liver Cleanse
Date:
April 19, 2007 04:17 PM
Complete Liver Cleanse Technical Data Sheet DESCRIPTION: The liver performs over 500 functions, including metabolizing carbohydrates and proteins, synthesizing and storing vitamins, and regulating hormones – naming just a few. To do this job, the liver is also required to be exposed to potentially harmful toxins and chemicals, every day. One way to support the liver is through periodic supplementation with the proper balance of herbal ingredients, phytosterols, and fiber. Complete Liver Cleanse is a convenient, multi-ingredient formula that supports overall liver health and detoxification. Complete Liver Cleanse: Includes ingredients for various aspects of liver and gallbladder support: -Herbal ingredients that support liver and gallbladder health -Detoxifying ingredients that keep bound toxins from being reabsorbed -Phytosterols to block cholesterol absorption in the intestines -Fiber that moves cholesterol and toxins out of the body -Oat beta-glucan fiber with up to 4 times higher viscosity than other beta-glucan Fibers -Simple, two week liver cleanse program FORMULA: Each 3 capsules contain: Calcium (as calcium D-glucarate) 13 mg Proprietary PuraFiber Blend: 1 mg Viscofiber Oat B-Gucan Concentrate, phytosterols (beta sitosterol, campesterol, stigmasterol, brassicasterol, and other plant sterols), and glucomannan Milk Thistle (Silybum marianum) Fruit Phytosome 220 mg One part Milk Thistle Extract, standardized to contain 80% Silymarin bound to two parts phosphatidylcholine (soy) using a patented process Burdock (Arctium lappa) Root Extract 4:1 100 mg Calcium D-Glucarate 100 mg Boldo (Peumus boldus) Leaf Extract 2:1 75 mg Turmeric (Curcuma longa) Rhizome Extract 50 mg Standardized to contain 90% curcuminoids Dandelion (Taraxacum offinale) Root Extract 4:1 50 mg Artichoke (Cynara scolymus) Leaf Extract 30 mg Standardized to contain 13-18% caffeylquinic Acids calculated as chlorogenic acid Contains no: sugar, salt, yeast, wheat, dairy products, artificial coloring, artificial flavoring, ingredients of animal origin, or preservatives. This product contains natural ingredients; color variations are normal. Other ingredients: See label for most current information Viscofiber is a registered trademark of Cebena Bioproducts, Inc. The use and composition of the Viscofiber proprietary formula is protected by patients and patent applications filed in the This product contains calcium D-glucarate, the use of which is licensed from Applied Food Sciences, LLC, and protected by HOW DOES IT WORK? The Liver Every day, the liver must process an almost unbelievable amount of blood – at a rate of three pints every minute. All the while, the liver performs over 500 physiologic functions, including protein and glucose synthesis, carbohydrate metabolism, vitamin and mineral storage, synthesis of clotting factors, urea formation, metabolism of medications, and the production of bile. The liver also assists in hormonal regulation, blood glucose control, and other regulatory functions. Harmful substances that have been neutralized by the liver are carried to the intestines and kidneys for excretion. They are transported by bile, a greenish, watery solution that is synthesized, and continuously being excreted, by the liver. Stored in the gallbladder, a small sac cupped in the under surface of the liver, bile is also required for the digestion of dietary fats. However, in the case of toxins, bile is primarily an early transporter of the toxic compounds to the intestines, where they can be bound to fiber that helps transport them out of the body. Environmental toxins, including lipid (fat) soluble toxins, are broken into water-soluble components by bile to be excreted through the kidneys or colon. Liver Detoxification Detoxification refers to the process of excreting potentially harmful compounds that are both generated by the body and acquired through exposure to the environment. In the body, toxins are generated as by-products of cellular metabolic processes. Examples include dead and digested bacteria, hydrogen peroxide, cellular debris, and carbon dioxide. The Environmental Protection Agency has determined that the amount of environmental toxins in the air, groundwater, and soil has increased significantly in the last 40 years. In fact, the use of pesticides has doubled every ten years since 1945. Americans are increasingly exposed to heavy metals, pesticides, fossil fuel emissions, sulfur oxides, hydrocarbons, and other harmful chemicals. The Environmental Protection Agency reports that traces of toxic chemicals can now be found in nearly every American. Herbal Liver Support One of the major components in Complete Liver Cleanse is its milk thistle extract, standardized to contain 80% silymarin, the plant’s most bioactive compound. Milk Thistle provides support, at a cellular level, for healthy liver function. A patented delivery system, known as the Phytosome process, provides superior absorption of the milk thistle extract. Silymarin, a key compound found in milk thistle, is a mixture of flavonoids with a long history of liver support. Silymarin supports the health of Kupffer cells, specialized liver cells responsible for removing bacteria, old blood cells, and other foreign matter from the liver’s blood supply. Silymarin scavenges free radicals (superoxide anion radical and nitric oxide) produced by activated Kupffer cells, supports healthy leukotriene levels, and supports glutathione production that is used in detoxification. Silymarin also supports the health of hepatocytes, highly versatile liver cells with unique physiologic functions. Studies of silymarin have demonstrated that it supports the health of the hepatocyte outer membrane, which is crucial to the liver’s detoxification processes. Silymarin also supports the healthy regenerative ability of the liver through support of protein synthesis in the hepatocytes. Phytosome Process A special, patented proves known as Phytosome enhances the absorption of milk thistle in Complete Liver Cleanse. The Phytosome process pairs herbal ingredients with phosphatidylcholine molecules. Phosphatidylcholine is a naturally occurring substance found in soybeans, egg yolks, and some vegetables. In the body, phosphatidylcholine is an important building block of cell membranes. When milk thistle (or other herbs) are bound with phosphatidylcholine, the phosphatidylcholine molecule facilitates absorption through the intestines into the bloodstream. Research has shown increased blood and serum levels for phytosome herbs in comparison to the individual herb alone. To test whether binding an herb with phosphatidylcholine increased its bioavailability, researchers gave volunteers identical amounts of either milk thistle alone, or milk thistle phytosome. The researchers then took blood sample from the participants and measured the level of silybin (a key compound in milk thistle). The measurements showed that silybin levels in participants taking the phytosome form of milk thistle were higher, and that silybin was detected for a longer time, than those who took milk thistle without the phytosome delivery system. Other Herbal Liver Supportive Ingredients Herbal extracts are often at their best when they are working synergistically – that is, when different constituents of each plant work together and support each other. Complete Liver Cleanse contains a variety of herbal extracts that have noted benefits for supporting the body’s healthy bile flow and free-radical scavenging effects. These ingredients provide a wide spectrum of liver supportive benefits. For instance, dandelion root extract supports healthy bile flow from the gallbladder. Burdock Root: Burdock is originally native to Europe and Asia, but was introduced to Burdock root (Arctium lappa) supports the natural physiologic processes of organs involved in detoxification and elimination: notably, the liver, kidneys, and intestines. Boldo: Bolodo (pemus boldus) is a small evergreen native to South America, but naturalized to southern In scientific studies, boldo appears to have strong free-radical scavenging ability, mostly attributed to the catechin and flavonoids content of its leaves. In a clinical study, boldo also appears to relax smooth muscle and support intestinal transit time. Artichoke Leaf extract specifically supports healthy bile production in the liver and healthy gastrointestinal function in general. Research into artichoke’s gastrointestinal supportive properties has included at least three clinical trials. Artichoke’s role in supporting healthy cholesterol levels within normal limits has also been investigated. Turmeric: Turmeric (Curcuma longa) is a perennial shrub native to southern More recently, turmeric has been investigated for its support of healthy bile secretion, and pancreatic and gastric function. In a scientific study, dietary curcuminoids derived from turmeric supported healthy lipid metabolism and cholesterol levels already within normal limits. Curcumin has also been shown in scientific studies to enhance the activity of glutathione S-transferase - an enzyme responsible for linking glutathione (one of the body’s natural antioxidants) with toxins to help remove them from the body. In this way, it provides additional support for healthy liver function. Detoxification Calcium d-glucarate: The process of detoxification is the breakdown and excretion of substances that are no longer needed or may be harmful to the body. One of the ways in which the body excretes hormones and toxins is by binding them to glucuronic acid in the liver, and then excreting this compound in the bile. However, this process can be disrupted by B-glucuronidase, an enzyme that is produced by intestinal bacteria. This enzyme has the ability to break (uncouple) the chemical bond established by glucuronic acid. This action releases the bound toxins, which are then reabsorbed into the body instead of being excreted. Calcium D-Glucarate is the calcium salt of d-glucaric acid. It is found in both the human body, and in some plant sources, including broccoli and oranges. Calcium d0glucarate enhances the body’s detoxification systems by inhibiting the actions of beta-glucuronidase. This helps decrease the portion of active compounds that could be hazardous to the body. Phytosterols Cholesterol is a waxy, fat-like substance that is vital to fat digestion, cell structure, nerve insulation and hormone production. Cholesterol comes from two sources: dietary or “exogenous” cholesterol absorbed in the intestine, and “endogenous” cholesterol formed mostly by the liver and stored in the gallbladder. Cholesterol occurs in two forms known as lipoproteins. Lipoproteins act as transports that carry fat s to and from the cells. High-density lipoprotein (HDL) carries low lipid density cholesterol (LDL) away from arterial walls and returns it to the bloodstream. LDL then travels back to the liver, which processes and eliminates it. While high levels of HDL cholesterol is desirable, high amounts of LDL cholesterol is not supportive of optimal health. LDL-cholesterol is both synthesized in the body, or absorbed into the bloodstream through receptor sites in the intestines. Think of these receptors as “parking spaces” for cholesterol. As it happens, the liver can receive up to 500 mg per day of cholesterol from intestinal absorption. (It can also produce as much as 1000 mg per day). One way to help reduce the absorption of LDL cholesterol molecules it to occupy their “parking places” in the intestines. Phytosterols in Liver Cleanse are essentially the “fat” of plants. They’re found in nuts, corn and rice and are some of the “good” fats associated with the benefits of olive oil, flaxseed oil and other healthy oils. The structure of phytosterols is so similar to cholesterol that they fit perfectly in the specially-shaped intestinal parking spaces that LDL-cholesterol would normally occupy. Taken with, or just before meals, phytosterols block the cholesterol receptor sites so that cholesterol is excreted from the body rather than absorbed. Phytosterols also have the additional role of helping promote healthy bile salt excretion in the intestines. The phytosterol blend in Complete Liver Cleanse can help minimize the absorption of cholesterol from high-protein food sources, help retain healthy cholesterol levels that are within normal limits, and move bile sat through the digestive system. Fiber and detoxification Fiber plays a key role in the removal and excretion of intestinal toxins in detoxification. Only fibers that can effectively bind toxins will be successful in eliminating these harmful substances. Due to the unique benefits of individual fibers, the best binding, removal, and elimination effects are noted when combining different fiber types. Complete Liver Cleanse contains a combination of oat beta-glucan and konjac fiber that has been shown in scientific studies to bind to bile salts. Dietary fibers are complex mixtures of cellulose, hemicellulose, pectin, mucilage, and gums, which are resistant to digestive fluids or enzymes – that is, they aren’t absorbed into the bloodstream. So, while fiber itself doesn’t necessarily provide nutrients, it does promote laxation and modulate gastric and intestinal physiology. Intestinal flora that normally reside within the colon utilize fiber as a medium for microbial fermentation, resulting in the synthesis of the vitamins, vitamin K and biotin, and the formation of short chain fatty acids, or SCFA. SCFA have a simple, but important job: to be absorbed by the colon mucosa, increasing fecal matter bulk and providing energy. Fiber has been demonstrated in numerous clinical studies to provide support of gastrointestinal, cardiovascular, immune, and endocrine function health. Complete Liver Cleanse also features two unique fibers to promote detoxification – konjac and oat beta-glucan. Konjac: Konjac, (Amorphophallus Konjac) is a tuber native to As a fiber, konjac has shown positive results maintaining healthy cholesterol levels within normal limits in clinical studies. This beneficial effect is due to konjac’s ability to boost excretion of bile acid. Oat beta-glucan: Oat beta-glucan has been a widely studied fiber source for supporting healthy cholesterol levels within normal limits. In a randomized clinical study, oat beta-glucan showed support of healthy HDL/LDL ratios already within normal limits in individuals over a three week trial. Closely linked to cholesterol, oat beta-glucan has also been studied for its support of healthy bile excretion. Fiber has benefits beyond maintaining healthy cholesterol levels already within normal limits. It also contributes to healthy blood sugar levels already within normal limits. In a double-blind, clinical study, the oat beta-glucan fiber used in Liver Cleanse was shown to have 4 times higher viscosity than another high concentrate beta-glucan fiber. Viscosity – the resistance to flow – is an important factor in beta-glucan, and all fiber. Water, for instance, would have a low viscosity, because it provides very little resistance to movement. Fiber, on the other hand, should have a higher viscosity in order to maximize its transit time through the GI tract, providing a gentle “scrubbing” on the intestinal walls. Therefore, the higher the viscosity, the greater the potential benefit. RECOMMENDATIONS: Three capsules in the morning and three capsules at bedtime for 14 days. LABEL PRECAUTION: Warnings: Do not use if you know or suspect you have an obstructed bile duct or problematic gallstones. If pregnant, nursing or taking prescription drugs, consult your healthcare practitioner prior to use. Keep out of reach of children.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1517) Mangoni - Complete SuperFruit Food 1oz equals 3 servings of Vegetables
Date:
December 27, 2006 12:26 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1440) Best Sugar Balance Svetol (green coffee extract)
Date:
May 05, 2006 06:30 PM
Ingredients Best Sugar Balance featuring Svetol® Svetol® is an extract of green coffee obtained by the use of a traditional patented extraction process from the beans of the species Coffea canephora robusta Pierre. This species is particularly rich in the constituent known as chlorogenic acid. Svetol® green coffee extract contains less than 2% caffeine. The extract is standardized to contain between 45-50% chlorogenic acids. In vitro (test tube) and in vivo research suggests that chlorogenic acids present in coffee may have the ability to regulate blood sugar concentrations after meals by acting on the intestinal absorption of glucose and improving the body's glucose tolerance. Clinical evidence also suggests that Svetol® green coffee extract may help to maintain a healthy blood sugar level when used as a part of the diet.* Benefits Maintains healthy blood sugar levels when used as a part of the diet* chlorogenic acidS chlorogenic acid is the major polyphenol compound found in Svetol® green coffee bean extract. In vitro and animal studies have been conducted to determine the potential actions of this polyphenol. Studies report that chlorogenic acid and related compounds have significant antioxidant potential and are responsible for the high reported antioxidant benefit of green coffee. Several studies suggest that consumption of coffee in the diet is one factor that is correlated to the maintenance of healthy neural function and healthy aging. Coffee has also been shown in vitro to suppress the production of various free radicals. The chlorogenic acid content of coffee has been determined to be a major factor in the free radical quenching properties of coffee. A study was conducted to assess the activity of coffee extracts against the production of hydroxyl radicals in an in vitro system. It was found that coffee extracts possessed significant suppressive activity against hydroxyl radicals. Of the compounds assumed to be responsible for this effect, the researchers concluded that the chlorogenic acids played a major role with some contributions from other compounds found in the extract. This compound may also strongly contribute to any potential neuroprotective effects seen with coffee consumption.1 Two further studies highlight a possible mechanism by which chlorogenic acid mediates its antioxidant activity. In one study, the FRAP (Ferric Reducing Antioxidant Power) assay was used to measure and compare the iron-reducing capacity of chlorogenic acid and caffeine. It was shown that the chlorogenic acid content of the samples tested was highly correlated with iron-reducing activity in this assay. Moreover, lighter roasted coffee samples (closer in nature to green coffee) had the highest iron-reducing activity. Caffeine did not influence the iron-reducing activity of the coffee samples.2 Iron compounds are known to mediate the production of radicals and often serve as catalysts for their production in the body. A second study shows that chlorogenic acid can bind to and Chelate certain iron compounds, preventing them from catalyzing radical-producing reactions. In this way, chlorogenic acid acts as a powerful antioxidant.3 chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health. Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee chlorogenic acid and related compounds have a dual effect on the production and suppression of free radicals. In the case of the hydroxyl radical, studies outlined previously suggest that chlorogenic acid suppresses the production of the radical due to its ability to chelate iron compounds, while other studies suggest that chlorogenic acid has direct scavenging effects on the hydroxyl radical.4 Dietary intake of this potent polyphenol may confer multiple benefits to human health. Several studies further suggest that chlorogenic acid in coffee can have a beneficial effect on blood sugar levels when consumed as a part of the diet. A recent study assessed the effects of coffee and tea consumption on glucose tolerance in middle-aged Japanese men. In this study, the relationship between daily intakes of green tea or coffee and glucose tolerance status was measured by the oral glucose tolerance test (OGTT). More than 3,400 men participated in the study in which fasting glucose was measured before and 2 hours after administration of an oral glucose load. A self-administered questionnaire was used to establish daily levels of dietary coffee and green tea consumption over the past year. The results showed that those individuals who consumed the highest levels of coffee per day had lower fasting glucose levels (by 1.5%) and lower post-test glucose concentrations (4.3% lower) than those who did not consume coffee on a daily basis. In this study, green tea consumption was not associated with any benefits on glucose concentrations.5 It is likely that the chlorogenic acid found in coffee plays a role in supporting healthy glucose metabolism, whereas the role of caffeine is not clear, with some reports suggesting an adverse effect on sugar metabolism. A second study further confirms an effect of chlorogenic acid at inhibiting the absorption of glucose from the diet. This effect occurs in the small intestine. In this study, nine healthy fasted volunteers consumed 25 grams of glucose in 400 ml of water (the control group), caffeinated coffee, or decaffeinated coffee. Frequent blood samples were taken over the next 3 hours. It was found that glucose and insulin concentrations were higher 30 minutes after the consumption of caffeinated coffee than with either decaffeinated coffee or control (water).While caffeine has specific biological effects on raising glucose levels and impacting insulin profiles, chlorogenic acid was shown to have an antagonistic effect on glucose transport. Previous studies have also shown that chlorogenic acid significantly delays glucose uptake from the small intestine.6 RESEARCH ON SVETOL® Svetol® is a unique extract of Coffea canephora robusta green coffee beans containing between 45 and 50% chlorogenic acids with less than 2% total caffeine concentration. As outlined above, many studies highlight the potential benefits of coffee compounds, including chlorogenic acid, for providing protection against free radicals and promoting healthy glucose metabolism. A number of other potential benefits have been discovered for these compounds. Svetol® has also been the subject of preliminary clinical studies that have shown exciting results. In a pilot study, the effect of Svetol® on sugar concentrations after meals was evaluated in 15 individuals. In the same trial, the longer-term effects of Svetol® on weight management were also evaluated. Blood sugar concentrations were measured on two separate occasions. Patients were administered an oral glucose tolerance test (OGTT) in which they consumed a standard amount of sugar and had their blood sugar levels measured 1 hour after sugar intake. The first measurement was made on day 1 prior to taking Svetol® and the second OGTT was performed on day 2, after beginning the Svetol® regimen in which one tablet (200 mg per tablet) was administered 3 times during the day. Patients were fasted for at least 8 hours prior to the testing. The results showed that Svetol® was able to reduce blood sugar concentrations in 60% of the subjects. The mean reduction of blood sugar concentration in these individuals was 50%. The treatment was continued following the same regimen for 6 weeks to assess the impact of Svetol® on weight. The average weight loss of the participants was 1.5 kg (3.3 lbs) over the treatment period. 7 Based on the studies mentioned above and other related research on the ingredients in Svetol®, scientists have proposed two mechanisms of action whereby Svetol® may influence the metabolism and processing of glucose. The first mechanism seems to be an inhibitory action on glucose absorption from the diet. Svetol® may affect the uptake of glucose in the small intestine by modulating factors needed for sugar absorption. The second mechanism relates to possible effects of Svetol® in the liver's ability to produce glucose. chlorogenic acids have been shown in vitro and in animal studies to modulate the effects of certain enzymes in the liver that catalyze the production of glucose. By having this dual effect on sugar absorption and sugar production, Svetol® is an effective product for maintaining healthy blood sugar levels when used as a part of the diet.* SAFETY Svetol® is a natural food extract from green coffee beans containing a standardized amount of chlorogenic acid. Studies have shown that chlorogenic acid (up to 500 mg/kg/day) given to pregnant rats from the 5th through 12th day of gestation caused no maternal or fetal mortality and no adverse effects on the nervous system. chlorogenic acids have also been shown to be non-mutagenic in tests on bacteria such as the Ames test. The LD50 of chlorogenic acids has been determined to be higher than 2500 mg/kg body weight. Svetol® is also extremely low in caffeine, with less than 2% caffeine contained in the extract, and is not expected to have any of caffeine's stimulant effects. Svetol® is extremely safe with no adverse effects having been reported while taking Svetol® at the recommended dosage.7 *This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease. Scientific References 1) Daglia M, Racchi M, Papetti A, Lanni C, Govoni S,Gazzani G. In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee. J Agric Food Chem.2004 Mar 24;52(6):1700-4. 2) Moreira DP, Monteiro MC, Ribeiro-Alves M, Donangelo CM, Trugo LC. Contribution of chlorogenic acids to the iron-reducing activity of coffee beverages. J Agric Food Chem. 2005 Mar 9;53(5):1399-402. 3) Kono Y, Kashine S,Yoneyama T, Sakamoto Y, Matsui Y, Shibata H. Iron chelation by chlorogenic acid as a natural antioxidant. Biosci Biotechnol Biochem. 1998 Jan;62(1):22-7. 4) Zang LY, Cosma G, Gardner H, Castranova V, Vallyathan V. Effect of chlorogenic acid on hydroxyl radical. Mol Cell Biochem. 2003 May;247(1-2):205-10. 5) Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, Mineshita M, Kono S. Coffee consumption and glucose tolerance status in middle-aged Japanese men.Diabetologia. 2004 Dec;47(12):2145-51. Epub 2004 Dec 15. 6) Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33.
7) Berkem.Text on Svetol®.Gardonne, France: November 2005.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1258) Vitaberry Plus + Super Fruit Antioxidant
Date:
December 07, 2005 05:43 PM
Vitaberry Plus +™ Super Fruit AntioxidantBy Nilesh Patel, NOW Quality Assurance, April 20, 2005 Why are FRUITS AND VEGETABLES important? “Diets rich in FRUITS AND VEGETABLES may reduce the risk of some types of cancer and other chronic diseases.”- National Cancer Institute. OXYGEN AND ANTIOXIDANTS As we all know, “Oxygen is critical to life,” but is itself a double-edged sword. While oxygen is necessary to sustain life and for natural defense against microbes, too much oxygen in our cells can lead to the production of “free radicals” (mitochondrial respiratory chain) or ROS (Reactive Oxygen Species). Free radicals come in many forms - singlet oxygen, hydrogen peroxide, superoxideperoxynitrite, to name a few - but all have one commonality. Each has an unpaired (unbalanced) electron, a situation it remedies by stealing an electron from a stable molecule. This sets off a domino effect of oxidation, a chain reaction that usually ends up damaging cellular integrity and compromising overall health. Nature has a defense system in place to protect these processes in the form of antioxidants. Whether endogenous (produced by the body, such as liver enzymes, SOD, coenzymes and sulfur-containing compounds) or exogenous (obtained through the diet, such as vitamins C & E, bioflavonoids, carotenes, etc.), antioxidants “quench” free radicals by donating an electron to stabilize a molecule, thus controling the chain reaction and stopping the oxidation “domino effect”. ANTIOXIDANT-RICH FOODS Research suggests that eating plenty of foods high in antioxidants helps to slow the processes associated with aging and protect against many chronic diseases. Maximizing one’s antioxidant power will enhance overall health. Fruit and vegetables contain both nutritive and non-nutritive factors that can affect oxidative damage and enzymatic defense and might contribute to redox (antioxidant and prooxidant) actions. A new “6-a-day” study looked into the effects of fruits and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers by The Danish Institute for Food and Veterinary Research in Denmark. The study found that fruits and vegetables increase erythrocyte glutathione peroxidase activity and resistance of plasma lipoproteins to oxidation more efficiently than do the nutritive factors (vitamins and minerals) that the fruits and vegetables are also known to contain. Certain berries, such as blackberries, also contain salicylates, which are also linked to heart health and prevention of atherosclerosis. The protective effects of fruits and vegetables intake on both heart disease death and deaths in general have previously been demonstrated but researchers at the Human Nutrition Research Center on Aging at Tufts University, Boston. Quercetin is an anti-oxidizing flavonoid found in many berries (such as cranberries, bilberries, blueberries, strawberries, etc.) and can prevent CVDs (coronary vascular diseases), according to a recent Finnish study. All these natural plant polyphenols are responsible for the colors of many red and purple berries, fruits, vegetables and flowers. GOVERNMENT GUIDELINES The new federal guidelines released earlier this year by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Agriculture (USDA) recommend eating more fruits and vegetables, combined, than any other food group -- five cups or about 10 servings a day for most adults. The amount of fruits and vegetables recommended has increased for men and women of every age. “Fruits and vegetables are the "good news" story of the new Dietary Guidelines for Americans for food-loving consumers, the industry and America's public health”, stated the Produce for Better Health Foundation (PBH). Eating a variety of colorful phytochemical-rich fruits and vegetables has been associated with lower risk of some chronic diseases such as cancer and heart disease. Many authoritative organizations such as the National Cancer Institute and The American Heart Association recommend getting phytochemicals from whole foods, such as fruits and vegetables, rather than from individual component supplements. The Scottish government is promoting healthy eating through a scheme designed to increase purchasing of fruit and nutritional foods. Scottish health minister Andy Kerr said, "This initiative shows that healthy eating can be good for customers and good for business." Scottish women are said to have the highest rates of death from lung cancer in the world as well as the highest rates in Europe for coronary heart disease. They also have low consumption of fruits and vegetables, shown in studies to help protect against some cancers and benefit heart health. ROS (Reactive Oxygen Species) Free radicals and oxygen free radicals play an important role in the development and progression of many brain disorders such as brain injury, neurodegenerative disease, and Down syndrome. Oxidative stress is an important factor in the etiology and pathogenesis of diabetes & is also linked to other host of degenerative health conditions. Fortunately, antioxidants are available to support the body’s defense and fight disease and aging. Examples of “Fast acting antioxidants” in the body (serum) are: uric acid (polyphenols), ascorbate, bilirubin, vitamin E (the later two are lipid soluble). Examples of “Slow acting antioxidants” are glucose, urea nitrogen etc. In short, free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by-products of normal cellular metabolism. Their deleterious effects are minimized in vivo (in the body) by the presence of antioxidant systems. How do Antioxidants work? Antioxidants are substances in plants that help maintain health. Antioxidants protect against damage to cells caused by too many “free oxygen radicals,” which form because of the effects of oxidation. Smoking, sunlight, heavy exercise, and pollution all increase oxidation in the body. Most people would benefit by eating more (five to nine or more servings) fruits and vegetables & colorful plant foods, such as purple, dark green, yellow, orange, blue, and red ones, each day. These have healthful pigments along with antioxidant nutrients such as vitamin C, carotenoids, beta-carotene, lycopene, lutein, zeaxanthin, vitamin E, selenium, flavonoids, and other beneficial substances. There are numerous ways in which these antioxidants affect, but can be explained in two groups: Alpha (a) Effects: This refers to the scavenging or neutralizing of free radicals. These effects do not change the way humans (or animals) feel. There are also no noticeable health, psychological or emotional benefits. While there are no obvious changes, increased total antioxidant intakes are associated with decreased tumor rates, prevention of heart attacks and increased longevity. Beta (ß) Effects: These are the changes on health, psychological or emotional state that you or others will notice. In this case, the antioxidant is affecting metabolic processes (enzymes) with consequent changes in the physical (improvement in joint movements, improved skin condition, tissue damage recovery), emotional (better ability to cope with stress) or psychological state (increased alertness). The ORAC value Because most of the active nutritional components in fruits and vegetables are antioxidants, accurate measurement of antioxidant activity serves as a good indicator of potential health benefit. Scientific opinion runs high that ORAC (Oxygen Radical Absorption Capacity) will eventually become a government standard of reference for overall daily fruits and vegetables intake. ORAC units are a measurement of the ability of food to stop oxidation. It is most generally expressed in terms of Trolox equivalent per gram (µmole Trolox equivalents (TE)/g). POPULATION DATA A survey done by the National Research Council indicates that only 10% of the US population consumes the recommended five servings of fruits and vegetables per day. The equivalent to eating 5 mixed servings of fruits and vegetables per day is about 1,670 ORAC units. Based on scientific evidence it is suggested that daily antioxidant intake should be increased to between 3,000 and 5,000 ORAC units per day, per human subject, in order to reach a significant antioxidant capacity in blood plasma and other tissues. WHAT IS NOW DOING TO HELP? In accord with our mission, “To provide value in products and services that empower people to lead healthier lives,” NOW® Foods is introducing an ALL-FRUIT-DERIVED antioxidant product called VitaBerry Plus +™ Super Fruit Antioxidant Vcaps (vegetarian capsules) (product number #3336). At time of manufacture this product provides an ORAC value of at least 2,500 units per serving from a full-spectrum antioxidant blend of fruits containing phytochemicals and phenolic compounds such as anthocyanins, proanthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol , many organic acids, resveratrol and vitamin C. VitaBerry Plus +™ is formulated with VitaBerry™ Hi-ORAC Fruit Blend [a proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry (Vaccinium angustifolium) extract, Grape (Vitis vinifera) & Grape seed extract, Raspberry (Rubus idaeus) & Raspberry seed extract, Cranberry (Vaccinium macrocarpon), Prune (Prunus domestica), Tart Cherry (Prunus cerasus), Wild Bilberry (Vaccinium myrtillus) extract & Strawberry (Fragaria virginia)], Hi-Active™ Orange (Citrus sinensis) and Pomegranate (Punica granatum) min. 40% ellagic acid fruit extract. One gram of VitaBerry™ Hi-ORAC Fruit Blend provides at least 6,000 ORAC units (i.e., µmole Trolox equivalents (TE)/g). (Also watch for an upcoming antioxidant product from NOW called Enzogenol® (Pinus radiata bark extract from New Zealand) with Rutin (a flavonoid from South American fruit of Dimorphandra mollis) and Grapeseed extract. IS IT EFFECTIVE? Total ORAC value includes both lipophilic and hydrophilic components. VitaBerry Plus +™ contains only water/hydroethanol based extracts and concentrated (100:1 to 125:1) freeze-dried fresh fruit blends, so the lipophilic ORAC value is mere 2-4% of the total ORAC value. Glutathione peroxidase is a selenium-containing enzyme that decreases cell death from brain injuries. It also acts as a critical first-line antioxidant defense on the airway (respiratory) epithelial surface against ROS and RNS (reactive nitrogen species. Genetics research has found that the glutathione S-transferase gene controls the onset of Alzheimer’s, Parkinson’s disease etc. Taking glutathione (GSH) itself as a supplement does not boost cellular glutathione levels, since it breaks down in the digestive tract before it reaches the cells. So glutathione precursor dietary supplements (such as NAC and GliSODin), along with fruits and vegetables, are effective in boosting intracellular levels of GSH. The lungs have a defense system against the ROS oxidants consisting of low molecular weight antioxidants such as GSH and intracellular enzymes such as SOD, catalase and glutathione peroxidase to protect against the toxic effects of oxidants generated within the cells. Some of the primary effects of VitaBerry Plus +™ against the common reactive free-radical species or ROS are as follows: - Superoxide dismutase-SOD (destroys Superoxide radicals),- Catalase (neutralizes peroxides), - Functions similar to reduced Glutathione (GSH), - Glutathione peroxidase enzyme (detoxifies peroxides, using GSH as a reducing agent), - Functions similar to Glutathione S-transferase (GST), - Nullifies Superoxide-generating NADH/NADPH oxidase system In conclusion More concentrated than fresh berries, with over 6000 ORAC units per gram, VitaBerry Plus +™ provides consumers with the antioxidant power of almost 15 servings per day of FRUITS AND VEGETABLES ina convenient vegetarian capsule form! VitaBerry™ PLUS +™ (# 3336) provides a powerful, convenient way to supplement diets that do not include sufficient fruit and vegetable antioxidants Selected References: USDA/HHS guidelines report at: etaryguidelines/dga2005/document/
ls.com/proprietary/pdf/VitaberryBrochure.pdf g Kaplan M., Hayek T. , Raz A., Coleman R. and Aviram M. Pomegranate juice supplementation to apolipoprotein E deficient mice with extensive atherosclerosis reduces macrophages lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. J. Nutr. 131: 2082-2089 (2001) Lars O Dragsted et. al., The 6-a-day study:effects if fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. American Journal of Clinical Nutrition, Vol. 79, No. 6, 1060-1072, June 2004 Fuhrman B. and Aviram M. Polyphenols and flavaonoids protects LDL against atherogenic modifications.In: Handbook of Antioxidants Biochemical, Nutritional and Clinical Aspects, 2nd Edition. Cadenas E & Packer L (Eds.) Marcel Dekker, NY(Pub.). 16:303-336 (2001) Wood, Jacqueline, et al. Antioxidant activity of procyanidin-containing plant extracts at different pHs. Food Chemistry 77 (2002) 155-161 Aviram M. Pomegranate juice as a major source for polyphenolic flavonoids and it is most potent antioxidant against LDL oxidation and atherosclerosis. Free Radical Research 36 (Supplement 1): 71-72 (2002) Jennifer Schraag, Antioxidants: Nature’s Way of Balancing Life. HSR Health Supplement Retailer, Vol. 11, No. 2, 24-27, February 2005 com/news/printNewsBis.asp?id=58665 com/news/printNewsBis.asp?id=58697
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=992) VitaBerry Plus+ Fact Sheet
Date:
December 07, 2005 05:38 PM
VitaBerry Plus+ Fact SheetNeil E. Levin, CCN, DANLA 3/18/05LIKELY USERS: Antioxidant users who want the best food source formula; People seeking polyphenols or ellagic acid supplements; Those who don’t eat fruit and want some of their benefits KEY INGREDIENTS: VitaBerry extract, Hi-Active Orange Extract, Pomegranate Extract (420 mg) (400 mg) (100 mg) MAIN PRODUCT FEATURES: This is a high antioxidant (high ORAC: 2,500 units per serving of oxygen radical absorbing capacity), proprietary blend of fruit extracts & concentrated powders containing Wild Blueberry extract, Grape & Grape seed extract, Raspberry & Raspberry seed extract, Cranberry, Prune, Tart Cherry, Wild Bilberry extract & Strawberry powder. Fortified with Hi-Active Orange Extract (Freeze-dried Orange (Citrus sinensis) powder with minimum of 40% vitamin C) and Pomegranate Extract (80% Polyphenols and 40% Ellagic Acid). Provides a broad-spectrum antioxidant blend with phytochemicals such as anthocyanins, chlorogenic acid, ellagic acid, quinic acid, resveratrol etc. in a single “0” size vegetarian capsule. There is a synergistic effect of mixing fruit antioxidants that provides antioxidant protection greater than is predicted by measuring each fruit source used in the mix individually. ADDITIONAL PRODUCT USE INFORMATION & QUALITY ISSUES: There will be some natural variation in color, taste and odor from these fruit sources. A special freeze drying technique preserves the antioxidant value of whole fruits in a concentrated form. SERVING SIZE & HOW TO TAKE IT: Serving is 2 Vcaps. Take one or more servings per day as an antioxidant supplement. May be taken with food or on an empty stomach (this is food). COMPLEMENTARY PRODUCTS: All antioxidants. CAUTIONS: Pregnant and lactating women and people using prescription drugs should consult their physician before taking any dietary supplement. This information is based on my own knowledge and references, and should not be used as diagnosis, prescription or as a specific product claim. This information has not been reviewed by the FDA or the company posting it. Information given here may vary from what is given on the product label because this page represents my understanding of the science underlying the formula and ingredients. When taking any new formula, use common sense and cautiously increase to the full dose over time. Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. REFERENCES: Bagchi D, Sen CK, Bagchi M, Atalay M. Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry (Mosc). 2004 Jan;69(1):75-80, 1 p preceding 75. Review. PMID: 14972022 Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB, Bickford PC. Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines. J Neurosci. 2002 Jul 15;22(14):6114-20. PMID: 12122072 Huang D, Ou B, Prior RL. The Chemistry behind Antioxidant Capacity Assays. J Agric Food Chem. 2005 Mar 23;53(6):1841-1856. PMID: 15769103 Kay CD, Holub BJ. The effect of wild blueberry (Vaccinium angustifolium) consumption on postprandial serum antioxidant status in human subjects. Br J Nutr. 2002 Oct;88(4):389-98. PMID: 12323088 Mazza G, Kay CD, Cottrell T, Holub BJ. Absorption of anthocyanins from blueberries and serum antioxidant status in human subjects. J Agric Food Chem. 2002 Dec 18;50(26):7731-7. PMID: 12475297 Prior RL, Cao G. Analysis of botanicals and dietary supplements for antioxidant capacity: a review. J AOAC Int. 2000 Jul-Aug;83(4):950-6. Review. PMID: 10995120 Prior RL, Cao G. In vivo total antioxidant capacity: comparison of different analytical methods. Free Radic Biol Med. 1999 Dec;27(11-12):1173-81. Review. PMID: 10641708 Prior RL, Hoang H, Gu L, Wu X, Bacchiocca M, Howard L, Hampsch-Woodill M, Huang D, Ou B, Jacob R. Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food samples. J Agric Food Chem. 2003 May 21;51(11):3273-9. PMID: 12744654 Proteggente AR, Pannala AS, Paganga G, Van Buren L, Wagner E, Wiseman S, Van De Put F, Dacombe C, Rice-Evans CA. The antioxidant activity of regularly consumed fruit and vegetables reflects their phenolic and vitamin C composition. Free Radic Res. 2002 Feb;36(2):217-33. PMID: 11999391 Roy S, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK. Anti-angiogenic property of edible berries. Free Radic Res. 2002 Sep;36(9):1023-31. PMID: 12448828 Sofic E, Rustembegovic A, Kroyer G, Cao G. Serum antioxidant capacity in neurological, psychiatric, renal diseases and cardiomyopathy. J Neural Transm. 2002 May;109(5-6):711-9. PMID: 12111462 Stintzing FC, Stintzing AS, Carle R, Frei B, Wrolstad RE. Color and antioxidant properties of cyanidin-based anthocyanin pigments. J Agric Food Chem. 2002 Oct 9;50(21):6172-81. PMID: 12358498
Wu X, Beecher GR, Holden JM, Haytowitz DB, Gebhardt SE, Prior RL. Lipophilic and hydrophilic antioxidant capacities of common foods in the United States. J Agric Food Chem. 2004 Jun 16;52(12):4026-37. PMID: 15186133
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=991) Liver and Digestive Support - Artichoke Extract.
Date:
September 13, 2005 06:32 PM
Artichokes have been used for digestive support and liver health since the Roman Empire in the 4th century B.C. and recently, scientists have begun documenting their scientific benefits. They discovered that compounds such as cynarin and chlorogenic acids support bile production, which helps stimulate healthy digestion, relieve occasional indigestion, increase fat metabolism, support liver health, improve gallbladder function and promote cholesterol wellness. Planetary Formulas Artichoke Extract is standardized to 5% cynarin and 15% chlorogenic acids.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=778) NEW PRODUCT ANNOUNCEMENT
Date:
July 05, 2005 06:29 PM
The Most Comprehensive Antioxidant Formula Available!
Four tablets contain: Vitamin A (as beta-carotene 8,500 IU & palmitate 4,000 IU) 12,500 IU
gamma-Vitamin E Complex 500 mg
Quercetin 100 mg
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=548) GREEN COFFEE EXTRACT - Powerful Natural Antioxidant 
Date:
June 29, 2005 11:06 AM
According to the National Coffee Association’s 2001 National Coffee Drinking Trends survey, 52 percent, or 107 million, U.S. adults drink coffee each day. Although you may already enjoy coffee as your favorite way to begin the morning, new studies are revealing its impressive health benefits. GREEN COFFEE EXTRACT (GCA®) is a newly discovered powerful antioxidant that helps protect against oxidative stress caused by free radicals - a major cause of accelerated aging. Source Naturals GREEN COFFEE EXTRACT (GCA®) is a patent-pending, all-natural green coffee bean extract derived from raw, unroasted coffee beans. It is high in chlorogenic and caffeic acids, two primary compounds responsible for its antioxidant activity. GREEN COFFEE EXTRACT is naturally low in caffeine and contains at least 65 percent total polyphenol antioxidants. The Coffee Story The history of coffee dates back more than a thousand years. Originally, coffee beans were used as food. East African tribes would grind the coffee berries together, mixing the results into a paste with animal fat. Later, around 1000 AD, Ethiopians made a type of wine from coffee berries, fermenting the dried beans in water. Coffee also grew naturally on the Arabian Peninsula where it was first developed into a hot drink. Despite decades of research on coffee and caffeine, there are many misconceptions about the potential health risks associated with coffee, while many of the beneficial aspects have gone unnoticed. Polyphenols: Powerful Antioxidants Phenolic compounds, or polyphenols, are a widespread family of compounds found in all plants including grapes, coffee and tea. They possess outstanding antioxidant and free radical scavenging properties, which may help defend cells and protect the body against the effects of aging. The high antioxidant activity observed in research on coffee is believed to be mostly due to the phenolic acids. GREEN COFFEE EXTRACT contains a number of polyphenols called hydroxycinnamic acids, with the two most prominent being chlorogenic and caffeic acids. Caffeic acid is the most abundant phenolic compound in coffee. In vitro and in vivo studies show that these acids protect against low-density lipoprotein (LDL) oxidation and lipid peroxidation. Glucose Metabolism There is accumulating evidence that certain dietary polyphenols, such as chlorogenic acid, may have biological effects in the small intestine that alter patterns of glucose uptake. chlorogenic acid has been shown to inhibit glucose 6 phosphate (Glc-6-Pase) activity. Glc-6-Pase is an enzyme that has a key role in regulating glucose metabolism. An in vivo study on rats demonstrated that chlorogenic acid improved glucose tolerance. Natural Wellness Nature provides us with special compounds that allow us to explore safe alternatives to support our health. Your local health food outlet is a great resource for nutritional education and effective, advanced natural products. Source Naturals is pleased to partner with these outlets to bring you innovative products like GREEN COFFEE EXTRACT.
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